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Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents

Lucas, Stephanie J, Lord, Rianne M, Wilson, Rachel L, Phillips, Roger M, Sridharan, Visuvanathar and McGowan, Patrick C (2012) Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents. Dalton Transactions, 41 (45). pp. 13800-13802. ISSN 1477-9226

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Abstract

Several Ru-arene and Ir–Cp* complexes have been prepared incorporating (N,N), (N,O) and (O,O) coordinating bidentate ligands and have been found to be active against both HT-29 and MCF-7 cell lines. By incorporating a biologically active ligand into a metal complex the anti-cancer activity is increased.

Item Type: Article
Subjects: R Medicine > RM Therapeutics. Pharmacology
Schools: School of Applied Sciences
Related URLs:
Depositing User: Roger Phillips
Date Deposited: 07 May 2015 12:31
Last Modified: 07 May 2015 12:31
URI: http://eprints.hud.ac.uk/id/eprint/24423

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