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Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands

Monteiro, DCF, Phillips, Roger, Crossley, BD, Fielden, J and Willans, CE (2012) Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands. Dalton Transactions, 41 (13). pp. 3720-3725. ISSN 1477-9226

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Abstract

A diverse library of cationic silver complexes bearing bis(N-heterocyclic carbene) ligands have been prepared which exhibit cytotoxicity comparable to cisplatin against the adenocarcinomas MCF7 and DLD1. Bidentate ligands show enhanced cytotoxicity over monodentate and macrocyclic ligands.

Item Type: Article
Subjects: R Medicine > RM Therapeutics. Pharmacology
Schools: School of Applied Sciences
Related URLs:
Depositing User: Roger Phillips
Date Deposited: 26 Feb 2015 16:31
Last Modified: 02 Dec 2016 05:25
URI: http://eprints.hud.ac.uk/id/eprint/23474

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