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VDAC: the wizard of mitochondrial OM

Mertins, Barbara, Psakis, Georgios and Essen, Lars-Oliver (2014) VDAC: the wizard of mitochondrial OM. Biological Chemistry, 395 (12). pp. 1435-1442. ISSN 1431-6730

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Voltage dependent anion channels (VDAC) are the most abundant proteins in the outer mitochondrial membrane. Although they are essential in metabolite exchange, cell defense and apoptosis, the molecular mechanism of these VDAC-mediated processes remains elusive. Here we review recent progress in terms of VDACs' structure and regulation with a special focus on the molecular aspects of gating and the interaction with effector proteins.

Item Type: Article
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Q Science > QH Natural history > QH301 Biology
Schools: School of Applied Sciences
Related URLs:
Depositing User: Georgios Psakis
Date Deposited: 02 Sep 2014 13:36
Last Modified: 01 Dec 2015 13:02


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