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Phylogeography of mitochondrial DNA in western Europe

Richardson, M., Macaulay, Vincent, Bandelt, Hans-Jürgen and Sykes, B.C. (1998) Phylogeography of mitochondrial DNA in western Europe. Annals of Human Genetics, 62 (3). pp. 241-260. ISSN 00034800

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For most of the past century, prehistorians have had to rely on the fossil and archaeological records in order to reconstruct the past. In the last few decades, this evidence has been substantially supplemented from classical human genetics. More recently, phylogenetic analyses of DNA sequences that incorporate geographical information have provided a high-resolution tool for the investigation of prehistoric demographic events, such as founder effects and population expansions. These events can be dated using a molecular clock when the mutation rate and founder haplotypes are known. We have previously applied such methods to sequence data from the mitochondrial DNA control region, to suggest that most extant mitochondrial sequences in western Europe have a local ancestry in the Early Upper Palaeolithic, with a smaller proportion arriving from the Near East in the Neolithic. Here, we describe a cladistic notation for mitochondrial variation and expand upon our earlier analysis to present a more detailed portrait of the European mitochondrial record.

Item Type: Article
Subjects: D History General and Old World > D History (General) > D051 Ancient History
D History General and Old World > D History (General) > D901 Europe (General)
Q Science > Q Science (General)
Q Science > QH Natural history > QH426 Genetics
Schools: School of Applied Sciences
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Depositing User: Sara Taylor
Date Deposited: 07 Aug 2014 10:19
Last Modified: 07 Aug 2014 10:19


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