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Piperolein B, isopiperolein B and piperamide C9:1(8E): total synthesis and cytotoxicities

Kayamba, Francis, Dunnill, Christopher, Hamnett, David J., Rodríguez, Arantxa, Georgopoulos, Nikolaos T. and Moran, Wesley J. (2013) Piperolein B, isopiperolein B and piperamide C9:1(8E): total synthesis and cytotoxicities. RSC Advances, 3 (37). pp. 16681-16685. ISSN 2046-2069

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Abstract

Total syntheses of the reported structures of piperolein B, isopiperolein B and piperamide C9:1(8E) have been achieved. The analytical data reported for piperolein B and piperamide C9:1(8E) match the synthetic values, however those for isopiperolein B do not. The cytotoxicities of these three structurally similar compounds against cancer cell lines of different tissue origins were evaluated and the results indicated that these compounds show differential effects on cancer cell viability.

Item Type: Article
Subjects: Q Science > QD Chemistry
Schools: School of Applied Sciences
Depositing User: Graham Stone
Date Deposited: 15 Aug 2013 13:39
Last Modified: 26 Aug 2016 02:16
URI: http://eprints.hud.ac.uk/id/eprint/18146

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