Murray, Paul M., Bower, John F., Cox, David K., Galbraith, Ewan K., Parker, Jeremy S. and Sweeney, Joseph B. (2013) A Robust First-Pass Protocol for the Heck–Mizoroki Reaction. Organic Process Research & Development, 17 (3). pp. 397-405. ISSN 1083-6160Metadata only available from this repository.
The Heck–Mizoroki (HM) reaction is one of the most widely used C–C bond-forming methods of contemporary synthesis. Notwithstanding this, these reactions frequently require significant optimization before efficient transformations can be obtained. We describe here the results of a study that aimed to establish a generic experimental protocol for HM reactions which enables acceptable yields from first-pass experiments. The methodology utilizes readily available stable catalysts and can be applied to a broad range of coupling partners.
|Subjects:||Q Science > QD Chemistry|
|Schools:||School of Applied Sciences|
|Depositing User:||Joseph Sweeney|
|Date Deposited:||01 May 2013 08:49|
|Last Modified:||01 May 2013 08:49|
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