Osborn, Helen, Howson, William and Sweeney, Joseph B. (1993) Ring-opening of n-tosyl aziridines by sulfur-stabilized nucleophiles. Synlett, 9. pp. 675-676. ISSN 0936-5214Metadata only available from this repository.
The novel ring-opening reaction of enantiopure N-activated aziridines 1 with anions 2 derived from 1,3-dithiane proceeds regiospecifically at the carbon of lesser substitution. The ring-opened products 3 may efficiently be converted to homochiral 2-tosylaminocarbonyl compounds 4.
|Subjects:||Q Science > QD Chemistry|
|Schools:||School of Applied Sciences|
|Depositing User:||Joseph Sweeney|
|Date Deposited:||17 Oct 2012 11:45|
|Last Modified:||17 Oct 2012 11:45|
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