Richecœur, Alexandre M.E. and Sweeney, Joseph B. (2000) Preparation of (+)-Hamabiwalactone B via Stille Coupling of an Enantiomerically Pure Stannylfuranone. Tetrahedron, 56 (3). pp. 389-395. ISSN 0040-4020Metadata only available from this repository.
An unambiguous and highly enantioselective total synthesis of the naturally occurring 2(5H)-furanone Hamabiwalactone B has been achieved. The key step was a palladium-catalysed cross coupling (“Stille” coupling) of the previously unreported stannylfuranone 2 with (E)-iodoalkene 3. The enantiomeric purity of the synthetic natural product was ≥99%, as judged by chiral HPLC.
|Subjects:||Q Science > QD Chemistry|
|Schools:||School of Applied Sciences|
|Depositing User:||Joseph Sweeney|
|Date Deposited:||18 Oct 2012 11:25|
|Last Modified:||18 Oct 2012 11:25|
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