Asymmetric synthesis of arylalanines via asymmetric aza-darzens (ADZ) reaction

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Maguire, Naomi, McLaren, Andrew and Sweeney, Joseph B. (2003) Asymmetric synthesis of arylalanines via asymmetric aza-darzens (ADZ) reaction. Synlett, 12. pp. 1898-1900. ISSN 0936-5214

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Official URL: http://dx.doi.org/10.1055/s-2003-41470

DOI: 10.1055/s-2003-41470

Abstract

(R)-3-Arylalanines may be prepared in high enantiomeric purity from N-dpp imines by a four-step reaction sequence involving asymmetric aza-Darzens reaction, dephosphinylation, hydrogenolysis and hydrolysis. The amino acids thus obtained were of >95% enantiomeric purity

Item Type:	Article
Subjects:	Q Science > QD Chemistry
Schools:	School of Applied Sciences
Related URLs:	Author
Depositing User:	Joseph Sweeney
Date Deposited:	18 Oct 2012 11:41
Last Modified:	18 Oct 2012 11:41
URI:	http://eprints.hud.ac.uk/id/eprint/15279

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