Preparation and ring-opening reactions of N,O-bis(diphenylphosphinyl) hydroxymethylaziridine (‘Di-Dpp’)

Tools

Sweeney, Joseph B. and Cantrill, Alex A (2003) Preparation and ring-opening reactions of N,O-bis(diphenylphosphinyl) hydroxymethylaziridine (‘Di-Dpp’). Tetrahedron, 59 (21). pp. 3677-3690. ISSN 0040-4020

Metadata only available from this repository.

Official URL: http://dx.doi.org/10.1016/S0040-4020(03)00551-9

DOI: 10.1016/S0040-4020(03)00551-9

Abstract

N,O-bis(diphenylphosphinyl)-2-(hydroxymethyl)aziridine (‘DiDpp’, 1) is efficiently prepared from 2-aminoethane-1,3-diol: this activated aziridine undergoes two sequential reactions with copper(I)-modified Grignard reagents, yielding α-branched N-Dpp amines in good yield.

Item Type:	Article
Subjects:	Q Science > QD Chemistry
Schools:	School of Applied Sciences
Related URLs:	Author
Depositing User:	Joseph Sweeney
Date Deposited:	18 Oct 2012 12:00
Last Modified:	18 Oct 2012 12:00
URI:	http://eprints.hud.ac.uk/id/eprint/15234

Item control for Repository Staff only:

View Item