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Synthesis and Characterization of Co-polymers Based on Methyl Methacrylate and 2-Hexyl Acrylate Containing Naphthopyrans for a Light-Sensitive Contact Lens

Nabais, Cláudia R. J. O. D., Heron, B. Mark, de Sousa, Hermínio C., Gil, Maria H. and Sobral, Abílio J. F. N. (2011) Synthesis and Characterization of Co-polymers Based on Methyl Methacrylate and 2-Hexyl Acrylate Containing Naphthopyrans for a Light-Sensitive Contact Lens. Journal of Biomaterials Science, Polymer Edition, 22 (1-3). pp. 139-152. ISSN 0920-5063

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Abstract

A series of novel transparent shape memory co-polymers, made from (meth)acrylate monomers, intended to be used as intraocular lens, was synthesized. The thermo-mechanical properties, shape memory properties and optical properties of the co-polymers could be adjusted by using monomers with various alkyl chain lengths. The cytocompatibility of the prepared co-polymers to L929 mouse connective tissue fibroblasts was demonstrated in vitro, and the co-polymers exhibited favorable cytocompatibility, supporting cell viability and proliferation. This study showed that the prepared co-polymers, which exhibited good flexibility, adjustable shape memory properties, high transparency and favorable cytocompatibility, could find great promising applications as intraocular lens.

Item Type: Article
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Schools: School of Applied Sciences
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Depositing User: Sharon Beastall
Date Deposited: 18 Sep 2012 12:00
Last Modified: 09 Oct 2012 09:19
URI: http://eprints.hud.ac.uk/id/eprint/14930

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