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Global hydrodynamic analysis of the molecular flexibility of galactomannans

Morris, Gordon, Patel, T. R., Picout, D. R., Ross-Murphy, S. B., Ortega, A., Garcia de la Torre, J. and Harding, S. E. (2008) Global hydrodynamic analysis of the molecular flexibility of galactomannans. Carbohydrate Polymers, 72 (2). pp. 356-360. ISSN 0144-8617

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In the past, intrinsic viscosity and sedimentation velocity analyses have been used separately to assess the conformation and flexibility of guar and locust bean gum galactomannans based on worm-like chain and semi-flexible coil models. Publication of a new global method combining data sets of both intrinsic viscosity and sedimentation coefficient with molecular weight, and minimising a target (error) function now permits a more robust analysis. Using this approach, values for the persistence length of (10 ± 2) nm for guar and (7 ± 1) nm for locust bean gum are returned if the mass per unit length ML is floated as a variable. Using a fixed mass per unit length based on the known compositional data of each galactomannan yields a similar value for Lp in both cases, (8 ± 1) nm for guar and (9 ± 1) nm for locust bean gum, with combined set of data yielding (9 ± 1) nm: within experimental error the flexibilities of both galactomannans are very similar. © 2007 Elsevier Ltd. All rights reserved.

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Item Type: Article
Uncontrolled Keywords: Galactomannan Guar LBG Mass per unit length Persistence length Semi-flexible coil Worm-like chain Data structures Hydrodynamics Mathematical models Robust control Viscosity Galactomannans Intrinsic viscosity Molecular flexibility Sedimentation Cyamopsis tetragonoloba
Subjects: Q Science > QD Chemistry
Schools: School of Applied Sciences
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Language of Original Document: English
Correspondence Address: Morris, G.A.; National Centre for Macromolecular Hydrodynamics, School of Biosciences, University of Nottingham, Sutton Bonington, Loughborough, LE12 5RD, United Kingdom; email:
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Depositing User: Gordon Morris
Date Deposited: 18 Sep 2012 13:32
Last Modified: 20 Aug 2015 01:03

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