Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM)

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Tan, T. H. Samuel, Hickman, David T., Morral-Cardoner, Jordi, Beadham, Ian G. and Micklefield, Jason (2004) Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM). Chemical Communications (5). pp. 516-517. ISSN 1359-7345

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Official URL: http://dx.doi.org/10.1039/B315768G

DOI: 10.1039/B315768G

Abstract

Adeninyl POM was prepared using solid-phase peptide chemistry and shown to exhibit higher affinity for complementary DNA and RNA than the corresponding adeninyl PNA.

Item Type:	Article
Additional Information:	This paper is dedicated to Professor Heinz G. Floss on the occasion of his 70th birthday.Electronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b3/b315768g/
Subjects:	Q Science > Q Science (General) Q Science > QD Chemistry
Schools:	School of Applied Sciences
Related URLs:	Author
Depositing User:	Sara Taylor
Date Deposited:	30 Jun 2011 11:38
Last Modified:	30 Jun 2011 11:38
URI:	http://eprints.hud.ac.uk/id/eprint/10843

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